ea0031s6.1 | Making the glucocorticoid clock run smoothly (Supported by Addison's Disease self-help group) | SFEBES2013
Weger Benjamin D
, Weger Meltem
, Diotel Nicolas
, Nusser Michael
, Rastegar Sepand
, Hirota Tsuyoshi
, Kay Steve A.
, Strahle Uwe
, Brenner-Weiss Gerald
, Dickmeis Thomas
Due to its rapid development and high fecundity, the zebrafish is a standard model in developmental biology and genetics. Furthermore, key hormone systems present in mammals are already active in zebrafish larvae. The endocrine system and the circadian clock are closely linked, and also the circadian system of zebrafish matures early in development. The small size of zebrafish larvae makes them particularly suitable for chemical screens in vivo: Larvae can be kept for...